Airway epithelial cell–pathogen interactions
نویسندگان
چکیده
منابع مشابه
Fungal glycan interactions with epithelial cells in allergic airway disease.
Human exposure to fungi results in a wide range of health outcomes, from invasive disease or allergy to immune tolerance. Inhaled fungi contact airway epithelial cells as an early event, and this host:fungal interaction can shape the eventual immunological outcome. Emerging evidence points to exposure to fungal cell wall carbohydrates in the development of allergic airway disease. Herein, we de...
متن کاملAdherence of airway neutrophils and inflammatory response are increased in CF airway epithelial cell-neutrophil interactions.
Persistent presence of PMN in airways is the hallmark of CF. Our aim was to assess PMN adherence, percentage of apoptotic airway PMN (aPMN), and IL-6 and IL-8 production when aPMN are in contact with airway epithelial cells. Before coculture, freshly isolated CF aPMN have greater spontaneous and TNF-alpha-induced apoptosis compared with blood PMN from the same CF patients and from aPMN of non-C...
متن کاملAdherence of airway neutrophils and inflammatory response is increased in CF airway epithelial cell-neutrophil interactions
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متن کاملAirway Epithelial Cell Migration Dynamics
Cell spreading and migration associated with the expression of the 92-kD gelatinase (matrix metalloproteinase 9 or MMP-9) are important mechanisms involved in the repair of the respiratory epithelium. We investigated the location of MMP-9 and its potential role in migrating human bronchial epithelial cells (HBEC). In vivo and in vitro, MMP-9 accumulated in migrating HBEC located at the leading ...
متن کاملInteractions of Aspergillus fumigatus Conidia with Airway Epithelial Cells: A Critical Review
Aspergillus fumigatus is an environmental filamentous fungus that also acts as an opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a life-threatening disseminated fungal infection. The infectious agents are inhaled conidia whose first point of contact is most likely to be an airway epithelial cell (AEC). The interaction between epithelial cells and conidi...
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ژورنال
عنوان ژورنال: Journal of Cystic Fibrosis
سال: 2004
ISSN: 1569-1993
DOI: 10.1016/j.jcf.2004.05.041